The pathophysiologic basis of nuclear medicine
Nuclear medicine is a medical specialty that uses radioactive tracers radiopharmaceuticals to assess bodily functions and to diagnose and treat disease. Specially designed cameras allow doctors to track the path of these radioactive tracers. Radioactive tracers are made up of carrier molecules that are bonded tightly to a radioactive atom.
These carrier molecules vary greatly depending on the purpose of the scan. For example, in cases where doctors need to know the exact source of intestinal bleeding, they may radiolabel add radioactive atoms to a sample of red blood cells taken from the patient.
Any accumulation of radioactivity in the intestines informs doctors of where the problem lies. For most diagnostic studies in nuclear medicine, the radioactive tracer is administered to a patient by intravenous injection.
However a radioactive tracer may also be administered by inhalation, by oral ingestion, or by direct injection into an organ. The mode of tracer administration will depend on the disease process that is to be studied. The 3D images are computer generated from a large number of projection images of the body recorded at different angles. SPECT imagers have gamma camera detectors that can detect the gamma ray emissions from the tracers that have been injected into the patient.
Gamma rays are a form of light that moves at a different wavelength than visible light. The cameras are mounted on a rotating gantry that allows the detectors to be moved in a tight circle around a patient who is lying motionless on a pallet. PET scans also use radiopharmaceuticals to create three-dimensional images.
A positron is a particle with roughly the same mass as an electron but oppositely charged. These react with electrons in the body and when these two particles combine they annihilate each other.
This annihilation produces a small amount of energy in the form of two photons that shoot off in opposite directions. The detectors in the PET scanner measure these photons and use this information to create images of internal organs. Click here to watch a short video about how PET scans work. SPECT scans are primarily used to diagnose and track the progression of heart disease, such as blocked coronary arteries.Skip to main content Skip to table of contents.
Chun K. Kim, Borys R. Krynyckyi, Josef Machac. Basis and Clinical Application of Brain Imaging. Basis of Antibody Imaging and Therapy. Arthur Z. Krasnow, Abdelhamid H. Elgazzar, Nafisah Kazem. Basis of Pediatric Genitourinary Imaging. Basis of Therapeutic Nuclear Medicine. Elgazzar, Abdullatif Al-Bader. Biological Effects of Ionizing Radiation. Back Matter Pages About this book Keywords Imaging Nuclear medicine Nuklearmedizin Pathologie Pathophysiologie Pathophysiology Radiotracers Scintigraphy Szintgraphie Tumor brain imaging cardiac function positron emission tomography.
Editors and affiliations. Elgazzar 1 1. Buy options.It considers the clinical problems of patients using available historical and laboratory data and then recommends a problem solving approach with nuclear medicine. The author is especially qualified to edit this textbook, as he is trained in both pathology and nuclear medicine. His depth of knowledge in the pathologic basis of disease and his many clinical insights are evident throughout this textbook.
This attractively designed and illustrated hardbound textbook contains 23 chapters of well-organized material that is clearly and succinctly written.
Medicine Pathology. Free Preview. Show next edition. Significantly enlarged new edition More clinically oriented details on scintigraphic studies Many new images, illustrations and tables see more benefits. Buy eBook. Buy Softcover. FAQ Policy. Reviews Radiology Review: " The Pathophysiologic Basis of Nuclear Medicine, second edition, is one of the most in-depth and comprehensive textbooks on nuclear medicine.
Show all. Inflammation Pages Elgazzar, Abdelhamid H. Adrenal Gland Pages Naddaf, Sleiman et al. Lymphoscintigraphy Pages Krasnow, Arthur Z. Show next xx. Read this book on SpringerLink. Recommended for you.
PAGE 1.Seller Rating:. About this Item: Hardcover. Condition: New. This book, now in its third edition, aims to promote a deeper understanding of the scientific and clinical basis of nuclear medicine and the new directions in medical imaging.
The new edit. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Seller Inventory More information about this seller Contact this seller 1. Language: English. Brand new Book. The new edition has been revised and updated to reflect recent changes and to ensure that the contents are in line with likely future directions. The book starts by providing essential information on general pathophysiology, cell structure and cell biology as well as the mechanisms of radiopharmaceutical localization in different tissues and cells.
The clinical applications of nuclear medicine are then presented in a series of chapters that cover every major organ system and relate the basic knowledge of anatomy, physiology and pathology to the clinical utilization of various scintigraphic modalities.
The therapeutic applications of nuclear medicine are discussed in a separate chapter, and the final chapter is devoted to the biologic effects of ionizing radiations, including radiation from medical procedures.
Seller Inventory SPR More information about this seller Contact this seller 2. Published by Springer About this Item: Springer, Condition: Brand New.
In Stock. Seller Inventory x More information about this seller Contact this seller 3. More information about this seller Contact this seller 4.Numerous and frequently-updated resource results are available from this WorldCat. Scholars Portal. SpringerLink Click for electronic access to e-book.
Please choose whether or not you want other users to be able to see on your profile that this library is a favorite of yours. Finding libraries that hold this item Furthermore, the book is suitable for an audience of experts, as well as doctors, researchers and students who wish to approach the world of nuclear medicine.
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Please enter your name. The E-mail message field is required. Please enter the message. Please verify that you are not a robot. Would you also like to submit a review for this item? You already recently rated this item.This book volume provides in depth coverage of the nucleic acid field and aims to represent a broad diversity of the methodologies and a wide range of nucleic-acid-related topics within the fields of molecular biology and biomedicine.
Chapters are divided in three sections detailing in vitro detection, nanotechnology and imaging, biomedical applications, and big data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. This book offers a practical and modern update on radioisotope therapy.
Clinically oriented, it provides a thorough guide to patient management, with the latest indications and procedures for the current radioisotopic treatments. It addresses the clinical problems associated with each respective pathology, discussing the management of patients diagnosis and non-radioisotope therapythe radiopharmaceuticals available today, and the current radioisotopic procedures.
Wherever possible, information on dosimetry is included at the end of each topic, together with a list of and comments on the most recent guidelines with their recommendations for radiometabolic therapy. The book is divided into six main sections: thyroid diseases, hepatic tumors HCC and hepatic metastasesbone metastases from prostate cancer, lymphomas, and neuroendocrine tumors. The last section is dedicated to new perspectives of radioisotope treatment. Based on contributions from of a multidisciplinary team of specialists: oncologists, surgeons, endocrinologists, hematologists, urologists, radiopharmacists and nuclear medicine physicians, it provides a comprehensive analysis of the position of radioisotope treatments among the various therapeutic options.
Readers interested in targeted therapy, radiometabolic therapy, radioimmunotherapy and radiometabolic imaging will find this book both informative and insightful.
This book, now in its third edition, aims to promote a deeper understanding of the scientific and clinical basis of nuclear medicine and the new directions in medical imaging. The new edition has been revised and updated to reflect recent changes and to ensure that the contents are in line with likely future directions. The book starts by providing essential information on general pathophysiology, cell structure and cell biology as well as the mechanisms of radiopharmaceutical localization in different tissues and cells.
The clinical applications of nuclear medicine are then presented in a series of chapters that cover every major organ system and relate the basic knowledge of anatomy, physiology and pathology to the clinical utilization of various scintigraphic modalities. The therapeutic applications of nuclear medicine are discussed in a separate chapter, and the final chapter is devoted to the biologic effects of ionizing radiations, including radiation from medical procedures.
This book explains clearly and in detail all aspects of radiation protection in nuclear medicine, including measurement quantities and units, detectors and dosimeters, and radiation biology. Discussion of radiation doses to patients and to embryos, fetuses, and children forms a central part of the book. Phantom models, biokinetic models, calculations, and software solutions are all considered, and a further chapter is devoted to quality assurance and reference levels.
Occupational exposure also receives detailed attention. Exposure resulting from the production, labeling, and injection of radiopharmaceuticals and from contact with patients is discussed and shielding calculations are explained. This is an ideal textbook for students and a ready source of useful information for nuclear medicine specialists and medical physics experts. This book will serve as the definitive source of detailed information on radiation, ionization, and detection in nuclear medicine.
It opens by considering fundamental aspects of nuclear radiation, including dose and energy, sources, and shielding. Subsequent chapters cover the full range of relevant topics, including the detection and measurement of radiation exposure with detailed information on mathematical modelling ; medical imaging; the different types of radiation detector and their working principles; basic principles of and experimental techniques for deposition of scintillating materials; device fabrication; the optical and electrical behaviors of radiation detectors; and the instrumentation used in nuclear medicine and its application.
The book will be an invaluable source of information for academia, industry, practitioners, and researchers. Remme, World Health Organisation, There are no specific aspects concerning physical, chemical or philosophical concepts and facts, but specificity does exist concerning geology, sociology and pathology.This book, now in its third edition, aims to promote a deeper understanding of the scientific and clinical basis of nuclear medicine and the new directions in medical imaging, which will lead to better utilization of nuclear medicine techniques in patient management and to further modifications and innovations in the field.
The new edition has been revised and updated to reflect recent changes and to ensure that the contents are in line with likely future directions.What is Nuclear Medicine and Molecular Imaging?
The book starts by providing essential basic information on general pathophysiology, cell structure, and cell biology as well as the mechanisms of radiopharmaceutical localization in different tissues and cells. The clinical applications of nuclear medicine are then presented in a series of chapters covering every major organ system.
These chapters relate the basic relevant knowledge of anatomy, physiology, and pathology to the clinical utilization of various scintigraphic modalities. The therapeutic applications of nuclear medicine, including recent advances, are discussed in a separate chapter. The final chapter is devoted to the biologic effects of ionizing radiations, including radiation from medical procedures. A glossary at the end of the book has been expanded with clear explanations of certain terms and uncommon disease conditions that will help students and trainees in understanding pertinent concepts.
The Pathophysiologic Basis of Nuclear Medicine. Editors view affiliations Abdelhamid H. Front Matter Pages i-xxi. Pathophysiology: General Principles. Pages The Cell and Tissue Biology. Basis of Radiopharmaceutical Localization. Abdelhamid H.
Elgazzar, Magda Elmonayeri. Nuclear Hematology. Kshitish Chandra Das, Abdelhamid H. Musculoskeletal System. Thyroid Gland. Parathyroid Gland. Elgazzar, Saud A. Adrenal Gland.
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